What is ?

PDRN (Polydeoxyribonucleotide), commonly known as Salmon DNA, is an advanced skincare ingredient being studied in regenerative dermatology for its potential to support skin renewal, improve hydration, and enhance the appearance of aging skin.

How does work?

PDRN (Polydeoxyribonucleotide) is a highly purified DNA-derived ingredient commonly obtained from salmon. It has attracted significant interest in regenerative medicine and cosmetic dermatology because of its role in supporting the skin's natural renewal processes.


Topical skincare products containing PDRN are being investigated for their ability to improve skin hydration, enhance skin texture, support the appearance of firmer skin, and reduce visible signs of aging. PDRN is frequently incorporated into premium anti-aging skincare formulations and professional cosmetic treatments.


In advanced skincare formulations, PDRN is often combined with Exosomes, Copper Peptides, Hyaluronic Acid, Growth Factors, and Ceramides to support overall skin quality.

Key benefits?

• Supports skin renewal


• Improves skin hydration


• Enhances skin texture


• Helps improve skin elasticity


• Reduces the appearance of fine lines


• Promotes a healthier-looking complexion


• Supports skin barrier function


• Complements advanced anti-aging skincare


• Suitable for most skin types

Clinical research

PDRN has been investigated in dermatology and regenerative medicine for its potential role in supporting skin quality and appearance. Early clinical studies suggest improvements in hydration, elasticity, and overall skin texture, although additional large-scale studies continue to evaluate its long-term cosmetic applications.

How to uses?

Topical PDRN cosmetic products are generally well tolerated when manufactured according to recognized quality standards. Individuals with sensitive skin should perform a patch test before first use. Product quality depends on ingredient source, purification process, and formulation.

References Scientific sources

International Journal of Molecular Sciences


Journal of Cosmetic Dermatology


Aesthetic Surgery Journal


Stem Cell Research & Therapy


PubMed – Polydeoxyribonucleotide (PDRN)


PubMed – PDRN in Dermatology


American Academy of Dermatology (AAD)

Recommendes Almoes products ?

ALMOES PDRN Repair Serum


ALMOES Advanced Repair Collection


ALMOES Anti-Aging Collection


ALMOES Professional Skincare Line